PXD018903-1

PXD018903 is an original dataset announced via ProteomeXchange.

Title	phospho-proteomic data on the LATS1 interactome from cells treated with two proapoptotic signals: FAS and etoposide
Description	Using this approach, we obtained phospho-proteomic data on the LATS1 interactome from cells treated with two proapoptotic signals: FAS and etoposide, which both activate LATS kinase activity [28].To identify the LATS1 interactome we transiently expressed GFP-LATS1 in HeLa cells, immunoprecipitated GFP-LATS1 with anti-GFP antibodies and identified the associated proteins using mass-spectrometry. Unspecific binding proteins were discarded by comparing with the control GFP IP.
HostingRepository	PRIDE
AnnounceDate	2021-09-09
AnnouncementXML	Submission_2021-09-09_00:28:39.131.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	David Matallanas
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-04-29 08:10:48	ID requested
⏵ 1	2021-09-09 00:28:40	announced

Quinn NP, Garc, í, a-Guti, é, rrez L, Doherty C, von Kriegsheim A, Fallahi E, Sacks DB, Matallanas D, IQGAP1 Is a Scaffold of the Core Proteins of the Hippo Pathway and Negatively Regulates the Pro-Apoptotic Signal Mediated by This Pathway. Cells, 10(2):(2021) [pubmed]

submitter keyword: Human, HeLa, LATS1

David Gomez
contact affiliation	Systems Biology Ireland, University College Dublin
contact email	david.gomez@ucd.ie
lab head
David Matallanas
contact affiliation	Systems Biology Ireland, University College Dublin
contact email	david.gomez@ucd.ie
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD018903
     1. Label: PRIDE project
     2. Name: phospho-proteomic data on the LATS1 interactome from cells treated with two proapoptotic signals: FAS and etoposide