PXD018736 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Characterization of human aging and Parkinson’s disease pre-frontal cortex by multi-omics: a glycomics, proteomics study. |
Description | This study identifies the age and PD related changes in glycans (HS and CS disaccharides) and proteomics in human aging and Parkinson’s disease. We analyzed the prefrontal cortex for changes in HS, CS and proteomic signatures in young versus aged as well as aged and PD in two cohorts. These studies provide insight into age- and PD changes in glycans and proteomics. We assess changes with PD and observe for pathways that may correlate with transcriptomics. We also observe in aging related proteomic changes and transcriptomics for changes in common with PD that may describe risk of disease. |
HostingRepository | PRIDE |
AnnounceDate | 2020-07-16 |
AnnouncementXML | Submission_2020-07-16_06:28:04.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Rekha Raghunathan |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-04-22 06:31:02 | ID requested | |
⏵ 1 | 2020-07-16 06:28:04 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: glycomic, proteomic, label-free proteomics, heparan sulfate, chondroitin sulfate, aging, Parkinson’s disease, pre-frontal cortex, multi-omics, mass spectrometry, hilic-wax, reverse phase, LC-MSMS. |
Contact List
Joseph Zaia |
contact affiliation | Biochemistry, Boston University |
contact email | jzaia@bu.edu |
lab head | |
Rekha Raghunathan |
contact affiliation | Boston University |
contact email | rrekha@bu.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/07/PXD018736 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD018736
- Label: PRIDE project
- Name: Characterization of human aging and Parkinson’s disease pre-frontal cortex by multi-omics: a glycomics, proteomics study.