PXD018458-1
PXD018458 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Arginine methylation of METTL14 promotes RNA N6-methyladenosine modification and endoderm differentiation of mouse embryonic stem cells |
Description | m6A is the most abundant modification of mRNA in mammals and plays an important role in human development and disease. METTL14 is a key component of m6A methyltransferase complex. The project showed that its post-translational arginine methylation can regulate the generation of m6A and the endoderm differentiation of mouse embryonic stem cells, indicating its essential function in the normal development of embryos. |
HostingRepository | iProX |
AnnounceDate | 2021-05-17 |
AnnouncementXML | Submission_2021-05-16_20:48:24.163.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Xiaona Liu |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | monomethylated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2020-04-10 00:32:45 | ID requested | |
⏵ 1 | 2021-05-16 20:48:24 | announced | |
2 | 2023-03-01 18:28:01 | announced | 2023-03-02: Update publication information. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: METTL14, arginine methylation, m6A, endoderm differentiation |
Contact List
Shan Xiao | |
---|---|
contact affiliation | Southern Medical University |
contact email | asdfg@smu.edu.cn |
lab head | |
Xiaona Liu | |
contact affiliation | Southern Medical University |
contact email | liuxn0406@163.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |