PXD018091-1

PXD018091 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteomics revealed modulation of macrophages by MetQ gene of Streptococcus suis serotype 2.
Description	MetQ gene of Streptococcus suis serotype 2 deletion strain has attenuated antiphagocytosis. However,the mechanism of antiphagocytosis and pathogenesis of MetQ in SS2 has remained unclear. In this study, stable isotope labeling by amino acids in cell culture (SILAC) based liquid chromatography-mass spectrometry (LC-MS) and subsequent bioinformatics analysis was used to determine differentially expressed proteins of RAW264.7 cells infected with △MetQ and ZY05719, aimed at elucidating the mechanism of antiphagocytosis and innate immunity of macrophages infected by Streptococcus suis.
HostingRepository	PRIDE
AnnounceDate	2021-09-09
AnnouncementXML	Submission_2021-09-09_00:07:48.667.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xiaomeng Pei
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-03-18 03:36:38	ID requested
⏵ 1	2021-09-09 00:07:49	announced
2	2024-10-22 05:28:00	announced	2024-10-22: Updated project metadata.

Pei X, Liu J, Liu M, Zhou H, Wang X, Fan H, Quantitative proteomics revealed modulation of macrophages by MetQ gene of Streptococcus suis serotype 2. AMB Express, 10(1):195(2020) [pubmed]

submitter keyword: mouse, RAW264.7 cell, SILAC, LC-MSMS

Hongjie Fan
contact affiliation	MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China
contact email	fhj@njau.edu.cn
lab head
Xiaomeng Pei
contact affiliation	Nanjing agricultural university
contact email	871318776@qq.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD018091

PRIDE project URI

• PRIDE
  1. PXD018091
     1. Label: PRIDE project
     2. Name: Quantitative proteomics revealed modulation of macrophages by MetQ gene of Streptococcus suis serotype 2.