PXD018029-2

PXD018029 is an original dataset announced via ProteomeXchange.

Title	Proteome mapping of human gingival tissue in health and disease
Description	Gingival tissue proteome is at the forefront of the periodontal research, yet have been hampered by lack of sufficient tissue-extraction methods. Using an emerging technology for tissue homogenization, pressure cycling technology (PCT), we characterize the gingival tissue proteomic profiles of both healthy (n=5) and disease (n=5) sites from five systemically healthy individuals (51.6± 4.3 years) with generalized chronic periodontitis. In brief, the tissue was lysed and digested in PCT, the peptide was further subjected to an Orbitrap Fusion mass spectrometer. Label-free quantification (LFQ) was performed by Progenesis QI using Mascot and Scaffold for identifying and sorting of protein conflict, respectively.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:12:40.289.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kai Bao
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue; deamidated residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2020-03-12 08:23:51	ID requested
1	2020-09-25 03:03:15	announced
⏵ 2	2024-10-22 05:12:40	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: Pressure cycling technology,Gingival tissue proteome, Chronic periodontitis

Nagihan Bostanci
contact affiliation	Division of Oral Diseases, Department of Dental Medicine, Karolinska Insitutet, Sweden
contact email	nagihan.bostanci@ki.se
lab head
Kai Bao
contact affiliation	postdoctoral researcher
contact email	kai.bao@ki.se
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD018029
     1. Label: PRIDE project
     2. Name: Proteome mapping of human gingival tissue in health and disease