PXD017671 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic changes of the liver in the absence of growth hormone (GH) actions |
Description | The liver is a central target organ of growth hormone (GH), which stimulates the synthesis of insulin-like growth factor 1 (IGF1) and affects multiple biochemical pathways. A systematic multi-omics analysis of GH actions in the liver has not been performed. GH receptor (GHR) deficiency is a unique model for studying consequences of lacking GH actions. In this study, we used molecular profiling techniques to capture a broad spectrum of these effects in the liver of a clinically relevant large animal model. |
HostingRepository | PRIDE |
AnnounceDate | 2020-03-30 |
AnnouncementXML | Submission_2020-03-30_00:07:24.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Thomas Fröhlich |
SpeciesList | scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-02-20 23:14:03 | ID requested | |
⏵ 1 | 2020-03-30 00:07:25 | announced | |
2 | 2020-06-12 04:12:55 | announced | 2020-06-12: Updated publication reference for PubMed record(s): 32277923. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Liver |
Growth hormone |
Laron syndrome |
Pig model |
Proteomics |
Contact List
Thomas Fröhlich |
contact affiliation | Laboratory for Functional Genome Analysis Genzentrum Ludwig-Maximilians-Universität München Feodor-Lynen-Str. 25 D-81377 München Germany |
contact email | frohlich@genzentrum.lmu.de |
lab head | |
Thomas Fröhlich |
contact affiliation | Laboratory for Functional Genome Analysis Gene Center Munich Ludwig-Maximilians-Universität Munich (LMU) Feodor-Lynen-Str. 25 81377 Munich Germany |
contact email | frohlich@genzentrum.lmu.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/03/PXD017671 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD017671
- Label: PRIDE project
- Name: Proteomic changes of the liver in the absence of growth hormone (GH) actions