PXD017518 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Cholesteryl α-D-glucoside 6-acyltransferase enhances the adhesion of Helicobacter pylori to gastric epithelium |
Description | Cellular locations of (Cholesteryl α-D-glucoside 6-acyltransferase) CGAT To study the cellular location of CGAT, based on our pervious experiments, the CGAT activity was observed in the outer membrane vesicles (OMVs), rather than in the culture medium, suggesting that CGAT resided in the outer membrane can be enclosed in the OMVs and secreted to the extracellular space. We then performed proteomic analysis for OMVs. Based on proteomic analysis, we found CGAT was present in the OMVs isolated from the strains of H. pylori 26695 and ΔCGT-knock-out, instead of ΔCGAT-knock-out strain. |
HostingRepository | PRIDE |
AnnounceDate | 2020-03-19 |
AnnouncementXML | Submission_2020-03-19_06:54:47.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD017518 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Hau-Ming Jan |
SpeciesList | scientific name: Helicobacter pylori 26695; NCBI TaxID: 85962; |
ModificationList | Oxidation; monohydroxylated residue; Carbamidomethyl; iodoacetamide derivatized residue |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-02-14 02:53:09 | ID requested | |
⏵ 1 | 2020-03-19 06:54:48 | announced | |
Publication List
Jan HM, Chen YC, Yang TC, Ong LL, Chang CC, Muthusamy S, Abera AB, Wu MS, Gervay-Hague J, Mong KT, Lin CH, -D-glucoside 6-acyltransferase enhances the adhesion of Helicobacter pylori to gastric epithelium. Commun Biol, 3(1):120(2020) [pubmed] |
Keyword List
submitter keyword: Helicobacter pylori, cholesteryl glucoside, acyltransferase, outer membrane vesicle, lipid raft, integrin |
Contact List
Chun-Hung Lin |
contact affiliation | Chun-Hung Lin's Lab, Institute of Biological Chemistry, Academia Sinica, No. 128 Academic Road Section 2, Nan-Kang, Taipei, 11529, Taiwan |
contact email | chunhung@gate.sinica.edu.tw |
lab head | |
Hau-Ming Jan |
contact affiliation | Institute of Biological Chemistry, Academia Sinica, No. 128 Academic Road Section 2, Nan-Kang, Taipei, 11529 |
contact email | escaflowne4928@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD017518
- Label: PRIDE project
- Name: Cholesteryl α-D-glucoside 6-acyltransferase enhances the adhesion of Helicobacter pylori to gastric epithelium