PXD017505-1

PXD017505 is an original dataset announced via ProteomeXchange.

Title	Autofluorescence positive and negative microglia constitute novel subsets found in healthy brain.
Description	Utilizing autofluorescence (AF) as a discriminating parameter, we identified two novel microglia subsets in both mice, termed autofluorescence-positive (AF+) and negative (AF-), and characterized them by label-free proteomics.
HostingRepository	PRIDE
AnnounceDate	2020-06-26
AnnouncementXML	Submission_2020-06-26_05:31:21.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dirk Walther
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2020-02-13 08:41:43	ID requested
⏵ 1	2020-06-26 05:31:21	announced
2	2024-10-22 05:08:00	announced	2024-10-22: Updated project metadata.

Burns JC, Cotleur B, Walther DM, Bajrami B, Rubino SJ, Wei R, Franchimont N, Cotman SL, Ransohoff RM, Mingueneau M, Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain. Elife, 9():(2020) [pubmed]

submitter keyword: microglia, autofluorescence, aging, lipofuscin, storage-bodies, autophagy

Dirk Walther
contact affiliation	Biogen Inc.
contact email	dirk.walther@biogen.com
lab head
Dirk Walther
contact affiliation	Biogen
contact email	dirk.walther@biogen.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/06/PXD017505

PRIDE project URI

• PRIDE
  1. PXD017505
     1. Label: PRIDE project
     2. Name: Autofluorescence positive and negative microglia constitute novel subsets found in healthy brain.