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PXD017505 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAutofluorescence positive and negative microglia constitute novel subsets found in healthy brain.
DescriptionUtilizing autofluorescence (AF) as a discriminating parameter, we identified two novel microglia subsets in both mice, termed autofluorescence-positive (AF+) and negative (AF-), and characterized them by label-free proteomics.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDirk Walther
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListiodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-02-13 08:41:43ID requested
12020-06-26 05:31:21announced
Publication List
Burns JC, Cotleur B, Walther DM, Bajrami B, Rubino SJ, Wei R, Franchimont N, Cotman SL, Ransohoff RM, Mingueneau M, Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain. Elife, 9():(2020) [pubmed]
Keyword List
submitter keyword: microglia, autofluorescence, aging, lipofuscin, storage-bodies, autophagy
Contact List
Dirk Walther
contact affiliationBiogen Inc.
contact emaildirk.walther@biogen.com
lab head
Dirk Walther
contact affiliationBiogen
contact emaildirk.walther@biogen.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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