PXD017244-1

PXD017244 is an original dataset announced via ProteomeXchange.

Title	Comprehensive cross-linking mass spectrometry reveals molecular insights into the between peripheral and core NuRD complex subunits
Description	Affinity purifications of different subunits of the NuRD complex, followed by cross-linking mass spectrometry (xIP-MS) to identify interaction domains. Six subunits and an interactor of NuRD were cross-inked with either BS3 or ADH/DMTMM and digested with either trypsin or chymotrypsin, to generate a dense cross-link network.
HostingRepository	PRIDE
AnnounceDate	2020-12-07
AnnouncementXML	Submission_2020-12-07_03:59:56.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Cornelia Spruijt
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ FT; LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2020-01-22 01:18:09	ID requested
⏵ 1	2020-12-07 03:59:56	announced

Dataset with its publication pending

submitter keyword: NuRD, xIP-MS, cross-linking, MBD, CHD

Michiel Vermeulen
contact affiliation	Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Oncode Institute, Radboud University Nijmegen, 6525 GA Nijmegen, The Netherlands
contact email	michiel.vermeulen@science.ru.nl
lab head
Cornelia Spruijt
contact affiliation	Radboud Universiteit Nijmegen
contact email	nellekespruijt@Hotmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/12/PXD017244

PRIDE project URI

• PRIDE
  1. PXD017244
     1. Label: PRIDE project
     2. Name: Comprehensive cross-linking mass spectrometry reveals molecular insights into the between peripheral and core NuRD complex subunits