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PXD016976-1

PXD016976 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMass Spectrometry-GUided Immunoassay DEvelopment (MS-GUIDE)
DescriptionWe applied targeted MS (parallel reaction monitoring, PRM) to pre-qualify candidates for clinical ELISA assay development. Literature harvested potential biomarker candidates, for which typically no antibodies for sensitive detection in complex samples exist, were evaluated in a medium-sized patient cohort using PRM. After biomarker validation, clinical grade ELISAs were developed and tested in a larger independent patient cohort.
HostingRepositoryPanoramaPublic
AnnounceDate2022-04-14
AnnouncementXMLSubmission_2022-04-14_19:20:21.319.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportsupported by repository but incomplete data and/or metadata
PrimarySubmitterSandra Goetze
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListDeamidated; Carbamidomethyl; Oxidation; Label:13C(6)15N(4); Label:13C(6)15N(2)
InstrumentOrbitrap Fusion ETD; Q Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-01-06 22:23:44ID requested
12022-04-14 19:20:21announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: prostate cancer, serum, glycocapture, biomarker, ELISA, PRM
Contact List
Bernd Wollscheid
contact affiliationETHZ
contact emailbernd.wollscheid@hest.ethz.ch
lab head
Sandra Goetze
contact affiliationETHZ
contact emailsgoetze@ethz.ch
dataset submitter
Full Dataset Link List
Panorama Public dataset URI