PXD016976-1

PXD016976 is an original dataset announced via ProteomeXchange.

Title	Mass Spectrometry-GUided Immunoassay DEvelopment (MS-GUIDE)
Description	We applied targeted MS (parallel reaction monitoring, PRM) to pre-qualify candidates for clinical ELISA assay development. Literature harvested potential biomarker candidates, for which typically no antibodies for sensitive detection in complex samples exist, were evaluated in a medium-sized patient cohort using PRM. After biomarker validation, clinical grade ELISAs were developed and tested in a larger independent patient cohort.
HostingRepository	PanoramaPublic
AnnounceDate	2022-04-14
AnnouncementXML	Submission_2022-04-14_19:20:21.319.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	supported by repository but incomplete data and/or metadata
PrimarySubmitter	Sandra Goetze
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	Deamidated; Carbamidomethyl; Oxidation; Label:13C(6)15N(4); Label:13C(6)15N(2)
Instrument	Orbitrap Fusion ETD; Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2020-01-06 22:23:44	ID requested
⏵ 1	2022-04-14 19:20:21	announced

Dataset with its publication pending

submitter keyword: prostate cancer, serum, glycocapture, biomarker, ELISA, PRM

Bernd Wollscheid
contact affiliation	ETHZ
contact email	bernd.wollscheid@hest.ethz.ch
lab head
Sandra Goetze
contact affiliation	ETHZ
contact email	sgoetze@ethz.ch
dataset submitter

Panorama Public dataset URI