PXD016966-1

PXD016966 is an original dataset announced via ProteomeXchange.

Title	Social isolation stress-resilient rats reveal energy metabolic shift in hippocampal nonsynaptic mitochondria
Description	We investigated the relative quantification of proteins in hippocampal cytosolic and nonsynaptic mitochondrial (NSM) fractions of rats exposed to chronic social isolation (CSIS), an animal model of depression, comparing CSIS-resilient with CSIS-sensitive or control rats, via a comparative subproteomic study. Our aim was to characterize the subproteome changes representing potential long-term changes in protein expression underlying the aforementioned conditions.
HostingRepository	PRIDE
AnnounceDate	2020-05-25
AnnouncementXML	Submission_2020-05-24_22:17:56.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Victor Costina
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	iodoacetamide derivatized residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2020-01-06 05:38:19	ID requested
⏵ 1	2020-05-24 22:17:57	announced
2	2024-10-22 05:04:21	announced	2024-10-22: Updated project metadata.

Filipovi, ć D, Peri, ć I, Costina V, Stanisavljevi, ć A, Gass P, Findeisen P, Social isolation stress-resilient rats reveal energy shift from glycolysis to oxidative phosphorylation in hippocampal nonsynaptic mitochondria. Life Sci, 254():117790(2020) [pubmed]

curator keyword: Biological

submitter keyword: rat, resilience, hippocampus, nonsynaptic mitochondria, LC-MS/MS, proteome

Peter Findeisen
contact affiliation	Institute for Clinical Chemistry, Medical Faculty Mannheim of the University of Heidelberg
contact email	Peter.Findeisen@medma.uni-heidelberg.de
lab head
Victor Costina
contact affiliation	Institute for Clinical Chemistry, Medical Faculty Mannheim of the University of Heidelberg
contact email	Victor.Costina@medma.uni-heidelberg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/05/PXD016966

PRIDE project URI

• PRIDE
  1. PXD016966
     1. Label: PRIDE project
     2. Name: Social isolation stress-resilient rats reveal energy metabolic shift in hippocampal nonsynaptic mitochondria