PXD016961-1

PXD016961 is an original dataset announced via ProteomeXchange.

Title	Characterization of Primary Patient B-cells under Various Stimulation Conditions
Description	The goal of this project was to compare the effects of differential stimulation of primary patient B-cells with CD40L, CpG, anti-IgM, and IL4 individually and in combination. Additionally, we observed a phenomenon where anti-IgM+CpG treatment resulted in a lymphoma-like phenotype and sought to compare this treatment regimen to the lymphoma cell line HBL-1.
HostingRepository	PRIDE
AnnounceDate	2025-08-21
AnnouncementXML	Submission_2025-08-21_15:02:51.688.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Joao Paulo
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2020-01-06 05:16:26	ID requested
⏵ 1	2025-08-21 15:02:52	announced

Dataset with its publication pending

curator keyword: Biological

submitter keyword: Human, IgM,B-cells, MS3, TMT, immunology, CD40L, HBL-1,SPS-MS3,CpG, IL4, 11-plex

Joao Paulo
contact affiliation	Cell Biology, Gygi Lab, Harvard medical School, Boston, MA
contact email	joao_paulo@hms.harvard.edu
lab head
Joao Paulo
contact affiliation	Harvard Medical School
contact email	joao_paulo@post.harvard.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD016961

PRIDE project URI

• PRIDE
  1. PXD016961
     1. Label: PRIDE project
     2. Name: Characterization of Primary Patient B-cells under Various Stimulation Conditions