PXD016708 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Native mass spectrometry of peptide-free and partially loaded MHC class I molecules |
Description | A disulfide-stabilized MHC class I molecule (HLA-A*02:01(Y84C/A139C), short dsA2) was characterized by native mass spectrometry. dsA2 was shown to be structurally intact in absence of any peptide whereas its wild type form was not. Furthermore, it was observed that the mutation did not disrupt the binding of cognate peptides. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-08 |
AnnouncementXML | Submission_2024-10-08_11:13:25.443.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Janine-Denise Kopicki |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q-Tof Ultima |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-12-11 07:42:47 | ID requested | |
⏵ 1 | 2024-10-08 11:13:25 | announced | |
Publication List
Keyword List
submitter keyword: peptide-binding, HLA-A, native MS,human, MHC class I |
Contact List
Charlotte Uetrecht |
contact affiliation | Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Germany; European XFEL GmbH, Germany |
contact email | charlotte.uetrecht@xfel.eu |
lab head | |
Janine-Denise Kopicki |
contact affiliation | CSSB Centre for Structural Systems Biology |
contact email | janine.kopicki@leibniz-hpi.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/05/PXD016708 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD016708
- Label: PRIDE project
- Name: Native mass spectrometry of peptide-free and partially loaded MHC class I molecules