PXD016658-1

PXD016658 is an original dataset announced via ProteomeXchange.

Title	Increased protein co-aggregation with amyloid in TRMT61A partial knock-out HeLa cells
Description	TRMT6/61A complex methylates N1-adenine in tRNAs and mRNAs. We analyzed disturbances of proteome homeostasis in human cells when N1-methyladenine (m1A) generation is disturbed due to the deficiency of TRMT61A.
HostingRepository	PRIDE
AnnounceDate	2025-09-03
AnnouncementXML	Submission_2025-09-03_06:17:44.738.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Giulia Calloni
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2019-12-09 01:59:51	ID requested
⏵ 1	2025-09-03 06:17:45	announced

10.3390/CELLS14171370;

curator keyword: Biological

submitter keyword: Amyloid, RNA methylation, protein aggregation

Martin R. Vabulas
contact affiliation	Goethe University Frankfurt
contact email	vabulas@em.uni-frankfurt.de
lab head
Giulia Calloni
contact affiliation	Goethe University Frankfurt
contact email	calloni@em.uni-frankfurt.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/09/PXD016658

PRIDE project URI

• PRIDE
  1. PXD016658
     1. Label: PRIDE project
     2. Name: Increased protein co-aggregation with amyloid in TRMT61A partial knock-out HeLa cells