PXD016608-1

PXD016608 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors
Description	Data contains results of LC-MS/MS analysis of KRAS4B-Q61H tyrosine phosphorylation following in vitro kinase reaction with Src kinase. Protein was denatured, reduced and alkylated and digested with Trypsin/Lys-C.
HostingRepository	MassIVE
AnnounceDate	2021-08-20
AnnouncementXML	Submission_2021-08-20_05:29:56.125.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Jonathan St-Germain
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	Deamidated; Acetyl; Oxidation; Carbamidomethyl; Phospho
Instrument	instrument model

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2019-12-04 08:16:36	ID requested
⏵ 1	2021-08-20 05:29:56	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: KRAS, LC-MS, tyorsine, phosphorylation, in vitro, kinase assay

submitter keyword: KRAS, LC-MS, tyorsine, phosphorylation, in vitro, kinase assay

Contact List

Brian Raught
contact affiliation	Princess Margaret Cancer Centre
contact email	brian.raught@gmail.com
lab head
Jonathan St-Germain
contact affiliation	Princess Margaret Cancer Centre
contact email	jonstgermain@gmail.com
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000084657/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000084657/