PXD016521 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic analysis of ∆4-CYB complex III mutant cybrids |
Description | The mitochondrial respiratory chain (MRC) enzymes associate in supercomplexes (SC). This structural interdependency may explain why defects in a single component often produce combined enzyme deficiencies in patients. A point in case is the alleged destabilization of complex I in the absence of complex III. To clarify the structural and functional relationships between complexes, we have used comprehensive proteomic, functional and biogenetical approaches to analyze a MT-CYB-deficient human cell line. |
HostingRepository | PRIDE |
AnnounceDate | 2020-01-07 |
AnnouncementXML | Submission_2020-01-07_10:55:00.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Erika Fernandez-Vizarra |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive; LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-11-29 02:37:53 | ID requested | |
⏵ 1 | 2020-01-07 10:55:05 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Human, Mitochondria |
Contact List
Massimo Zeviani |
contact affiliation | Medical Research Council-Mitochondrial Biology Unit. University of Cambridge, UK. |
contact email | mdz21@mrc-mbu.cam.ac.uk |
lab head | |
Erika Fernandez-Vizarra |
contact affiliation | MRC-Mitochondrial Biology Unit |
contact email | emfvb2@mrc-mbu.cam.ac.uk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD016521
- Label: PRIDE project
- Name: Proteomic analysis of ∆4-CYB complex III mutant cybrids