PXD016489-1

PXD016489 is an original dataset announced via ProteomeXchange.

Title	A potential study model seeking for proteins related to dental implant failure of type 2 diabetic patients estabilished by proteomics.
Description	Type 2 diabetes mellitus(T2DM)patients are a concern for dentists due to the lower success rate of healing period implant treatment. Here, we firstly calculated the success rate of in the healing period of diabetic and non-diabetic patients in the implant center of our hospital.Then we investigated the potential risk factors by proteomics analysis of 5 T2DM implant faliure patients in our implant center and compared the difference between high glucose induction study model and mesenchymal stem cell model from diabetic patients. The results suggested that the significantly higher implant failure rates in the T2DM group and the cell models derived from patients can be more comprehensive and accurate in reflecting the exact situation of BMSCs in patients with diabetes.
HostingRepository	PRIDE
AnnounceDate	2021-11-02
AnnouncementXML	Submission_2021-11-02_04:45:04.972.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yifan Xu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2019-11-28 02:42:14	ID requested
⏵ 1	2021-11-02 04:45:05	announced
2	2024-10-22 05:29:53	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: type 2 diabetes mellitus,dental implant, proteomics, bone marrow mesenchymal stem cells, high glucose

Jun li
contact affiliation	Beijing stomatology hospital, capital medical university
contact email	dgdxyf813@126.com
lab head
Yifan Xu
contact affiliation	Beijing Stomatology Hospital
contact email	dgdxyf813@126.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/11/PXD016489

PRIDE project URI

• PRIDE
  1. PXD016489
     1. Label: PRIDE project
     2. Name: A potential study model seeking for proteins related to dental implant failure of type 2 diabetic patients estabilished by proteomics.