PXD016412 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Influenza virus infection leads to global cardiac proteome remodeling during convalescence |
Description | Influenza virus infection leads to global cardiac proteome remodeling during convalescence MTD project_description "Influenza virus infections lead to more than 500,000 hospitalizations in the U.S. every year. Patients with cardiovascular diseases have been shown to be at high risk of influenza mediated cardiac complications. Importantly, recent reports have provided clinical data supporting a direct link between laboratory-confirmed influenza virus infection and adverse cardiac events. However, the molecular mechanisms of how influenza virus infection induces detrimental cardiac changes, even after resolution of the pulmonary infection, is completely unknown. We performed global quantitative proteomics as well as phosphoproteomics in this study. |
HostingRepository | PRIDE |
AnnounceDate | 2022-05-25 |
AnnouncementXML | Submission_2022-05-25_04:21:56.008.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yanbao Yu |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | phosphorylated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-11-24 23:43:56 | ID requested | |
⏵ 1 | 2022-05-25 04:21:56 | announced | |
Publication List
Lin YH, Platt MP, Gilley RP, Brown D, Dube PH, Yu Y, Gonzalez-Juarbe N, Influenza Causes MLKL-Driven Cardiac Proteome Remodeling During Convalescence. Circ Res, 128(5):570-584(2021) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: Influenza virus |
murine heart |
proteomics |
phosphorylation |
Contact List
Norberto Gonzalez-Juarbe |
contact affiliation | J. Craig Venter Institute, Rockville, MD 20850 |
contact email | NGonzale@jcvi.org |
lab head | |
Yanbao Yu |
contact affiliation | J. Craig Venter Institute |
contact email | yayu@jcvi.org |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
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[ - ]
- PRIDE
- PXD016412
- Label: PRIDE project
- Name: Influenza virus infection leads to global cardiac proteome remodeling during convalescence