PXD016208-1

PXD016208 is an original dataset announced via ProteomeXchange.

Title	Identification of changes in posttranslational modifications of EGFR and in EGFR-binding partners in head and neck cancer cells upon treatment with EGF or the EGFR antibody mixture Sym004
Description	This study aimed at determining the proteins that interact with EGFR and the changes in post-translational modifications within them.
HostingRepository	PRIDE
AnnounceDate	2024-10-08
AnnouncementXML	Submission_2024-10-08_13:49:03.680.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Silvia Surinova
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	ubiquitinylated lysine; phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-11-08 04:07:02	ID requested
⏵ 1	2024-10-08 13:49:04	announced

10.1038/s41598-019-57153-9;

Jones S, King PJ, Antonescu CN, Sugiyama MG, Bhamra A, Surinova S, Angelopoulos N, Kragh M, Pedersen MW, Hartley JA, Futter CE, Hochhauser D, Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation. Sci Rep, 10(1):663(2020) [pubmed]

submitter keyword: Human, EGFR, LC-MS/MS

Silvia Surinova
contact affiliation	Proteomics Research Translational Technology Platform, Cancer Research UK-UCL Centre, UCL Cancer Institute, University College London, UK ( lab head )
contact email	s.surinova@ucl.ac.uk
lab head
Silvia Surinova
contact affiliation	UCL
contact email	s.surinova@ucl.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/05/PXD016208

PRIDE project URI

• PRIDE
  1. PXD016208
     1. Label: PRIDE project
     2. Name: Identification of changes in posttranslational modifications of EGFR and in EGFR-binding partners in head and neck cancer cells upon treatment with EGF or the EGFR antibody mixture Sym004