PXD016177-2

PXD016177 is an original dataset announced via ProteomeXchange.

Title	Proteomics analysis of the second-generation merozoites of Eimeria tenella under Nitromezuril and Ethanamizuril stress
Description	Eimeria tenella is a high pathogenic coccidian that causes avain coccidiosis. Both Nitromezuril(NZL) and Ethanamizuril(EZL) are novel triazine compounds with high anticoccidial activity, but the mechanisms of their action are still unclear. This study explored the response of E.tenella to NZL and EZL by the study of changes in protein composition of the second-generation merozoites using label free quantification proteomics.After drug treatment, the merozoites were analyzed by LC-MS/MS. The identified proteins were annotated and analyzed by Gene ontology, Kyoto Encyclopedia of Genes and Genomes pathway and Protein-protein interaction networks analysis.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:58:22.774.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	李 雪雁
SpeciesList	scientific name: Coccidia; NCBI TaxID: NCBITaxon:5796; scientific name: Eimeria tenella; NCBI TaxID: 5802;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-11-06 07:50:39	ID requested
1	2020-01-09 02:40:43	announced
⏵ 2	2024-10-22 04:58:23	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: Ethanamizuril, label free quantification,Eimeria tenella, the second-generation merozoites, Nitromezuril

Fei-qun Xue
contact affiliation	Shanghai Veterinary Research Institute
contact email	fqxue@shvri.ac.cn
lab head
李 雪雁
contact affiliation	上海兽医研究所
contact email	932040693@qq.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD016177
     1. Label: PRIDE project
     2. Name: Proteomics analysis of the second-generation merozoites of Eimeria tenella under Nitromezuril and Ethanamizuril stress