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PXD015903-2

PXD015903 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCPTAC, TCGA Cancer Proteome Study of Ovarian Tissue
DescriptionExplore This Study at the NCI Proteomic Data Commons

Global proteome data have been acquired for 174 TCGA ovarian cancer tumor samples by 2 Proteome Characterization Centers (PCCs), Pacific Northwest National Laboratory (PNNL) and Johns Hopkins University (JHU). Both PCCs used iTRAQ (isobaric Tags for Relative and Absolute Quantification) protein quantification methods. Thirty-two of the 174 TCGA tumor samples were assayed at both sites yielding a total of 206 proteome characterizations. Glycoproteome (122 tumors) and phosphoproteome (69 tumors) analyses were also conducted, at JHU and PNNL respectively.

Information on the complete TCGA Ovarian Serous Cystadenocarcinoma (OV) cohort can be found here.
The Cancer Genome Atlas Research Network published on the Genomic characterization of the OV cohort in Nature on June 30, 2011

Genomic data for the 174 TCGA samples used in the CPTAC Proteome study can be downloaded from here.
HostingRepositoryMassIVE
AnnounceDate2019-10-25
AnnouncementXMLSubmission_2019-10-25_08:23:10.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterChristopher Kinsinger
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListCarbamidomethyl; Oxidation; Deamidated; Glu->pyro-Glu; Gln->pyro-Glu; Phospho; iTRAQ4plex
InstrumentLTQ Orbitrap Velos; Q Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-10-18 08:57:04ID requested
12019-10-23 17:39:52announced
22019-10-25 08:23:10announced2016-10-25: Updating description
Publication List
no publication
Keyword List
submitter keyword: CPTAC
Contact List
Hui Zhang
contact affiliationDepartment of Pathology, School of Medicine, Johns Hopkins University
contact emailhuizhang@jhu.edu
lab head
Richard Smith
contact affiliationPacific Northwest National Laboratory
contact emaildick.smith@pnnl.gov
lab head
Christopher Kinsinger
contact affiliationNIH/NCI
contact emailChristopher.kinsinger@nih.gov
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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