PXD014936-1

PXD014936 is an original dataset announced via ProteomeXchange.

Title	Complexome profiling of mitochondrial protein complexes from patients with mutation in NDUFC2 gene
Description	NDUFC2 is a subunit of the membrane part of NADH:ubiquinone oxidoreductase (complex I). Here we used complexome profiling to study the role of NDUFC2 in complex I stability and assembly.
HostingRepository	PRIDE
AnnounceDate	2020-08-10
AnnouncementXML	Submission_2020-08-10_04:30:00.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ilka Wittig
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-08-08 01:41:06	ID requested
⏵ 1	2020-08-10 04:30:00	announced
2	2020-09-29 23:29:07	announced	2020-09-30: Updated publication reference for PubMed record(s): 32969598.
3	2024-10-22 05:10:30	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: LC-MSMS, complexome profiling, oxidative phosphorylation system, complex I assembly

Robert Taylor
contact affiliation	(Head, NHS Highly Specialised Mitochondrial Diagnostic Laboratory and Professor of Mitochondrial Pathology), Wellcome Centre for Mitochondrial Research, Newcastle University, UK
contact email	robert.taylor@ncl.ac.uk
lab head
Ilka Wittig
contact affiliation	Functional Proteomics, Goethe University, Frankfurt am Main , Germany
contact email	wittig@med.uni-frankfurt.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/08/PXD014936

PRIDE project URI

• PRIDE
  1. PXD014936
     1. Label: PRIDE project
     2. Name: Complexome profiling of mitochondrial protein complexes from patients with mutation in NDUFC2 gene