PXD014908-1

PXD014908 is an original dataset announced via ProteomeXchange.

Title	SILAC of HepG2 or HepAD38 cell lines with HBV
Description	Hepatitis B Virus constitutes a major threat to global public health by infecting hepatocytes, initiating and driving the progress to end-stage liver disease and liver cancer. Curing treatment for HBV infection is yet unavailable, mainly due to unmet gaps in current understanding of HBV-host interaction. Here, multi-omics interrogations were conducted to generate the first landscape of HBV-induced global changes in host transcriptome, translatome and proteome, which identified multiple translatomic events that HBV orchestrated to remodel host proteostasis networks and afford micro-environments essential for HBV proliferation and persistence.
HostingRepository	PRIDE
AnnounceDate	2021-03-06
AnnouncementXML	Submission_2021-03-05_22:01:34.574.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Menghuan Zhang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2019-08-05 02:19:52	ID requested
⏵ 1	2021-03-05 22:01:35	announced
2	2024-10-22 05:19:44	announced	2024-10-22: Updated project metadata.

Yuan S, Liao G, Zhang M, Zhu Y, Wang K, Xiao W, Jia C, Dong M, Sun N, Walch A, Xu P, Zhang J, Deng Q, Hu R, Translatomic profiling reveals novel self-restricting virus-host interactions during HBV infection. J Hepatol, 75(1):74-85(2021) [pubmed]

ProteomeXchange project tag: Liver (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project

submitter keyword: human cell,HBV,SILAC

Ronggui Hu
contact affiliation	Chinese Academy of Sciences University,Center for Excellence in Molecular & Cellular Sciences, State Key Laboratory of Molecular Biology, Institute of Biochemistry & Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Rd., Shanghai, China 200031
contact email	coryhu@sibcb.ac.cn
lab head
Menghuan Zhang
contact affiliation	Chinese Academy of Sciences
contact email	zhangmenghuan1990@126.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/03/PXD014908

PRIDE project URI

• PRIDE
  1. PXD014908
     1. Label: PRIDE project
     2. Name: SILAC of HepG2 or HepAD38 cell lines with HBV