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PXD014729-1

PXD014729 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHuman pluripotent stem cell differentiation into hepatocyte-like cells in microfluidics: secretome and intracellular proteome.
DescriptionHuman pluripotent stem cells (both embryonic and induced pluripotent by reprogramming) were differentiated into hepatic-like cells inside microfluidic culture chambers and in conventional culture systems. Conditioned media and cell lysates were harvested and analyzed. Before starting the differentiation protocol, cells were labeled with the technique "stable isotope labeling with amino acids in cell culture" (SILAC). Then, heavy cells were used in microfluidics and light cells were used in conventional culture system for a relative quantitative comparison.
HostingRepositoryMassIVE
AnnounceDate2026-01-13
AnnouncementXMLSubmission_2026-01-13_02:47:58.655.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterCamilla Luni
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListLabel:13C(6)15N(2); Label:13C(6)15N(4); Acetyl; Oxidation
InstrumentOrbitrap Fusion ETD
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-07-24 00:45:11ID requested
12026-01-13 02:47:59announced
Publication List
no publication
Keyword List
submitter keyword: microfluidics, pluripotent stem cell, hepatic differentiation, microenvironment
Contact List
Nicola Elvassore
contact affiliationShanghaiTech University
contact emailnicola.elvassore@gmail.com
lab head
Camilla Luni
contact affiliationUniversity of Bologna
contact emailcamilla.luni@unibo.it
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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