PXD014695 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | α-arrestin-dependent endocytosis after cycloheximide treatment |
Description | To identify new plasma membrane (PM) proteins that require α-arrestins for endocytosis, we performed an iTRAQ-based quantitative proteomic screening. We analysed and compared the PM proteome for each arrestin knockout (art∆) strain to a WT strain after a 90 min cycloheximide (CHX) treatment. CHX is a translation inhibitor and can trigger the endocytosis of several transporters in a substrate-independent manner. We searched for proteins that underwent CHX-induced endocytosis in a WT strain but that remained stabilized at the PM in an art∆ strain. |
HostingRepository | PRIDE |
AnnounceDate | 2019-09-25 |
AnnouncementXML | Submission_2019-09-25_11:51:31.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jérôme Savocco |
SpeciesList | scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932; |
ModificationList | methylthiolated residue; iTRAQ8plex-116 reporter+balance reagent acylated residue |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-07-22 06:46:27 | ID requested | |
⏵ 1 | 2019-09-25 11:51:32 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: endocytosis, arrestin, cycloheximide, plasma membrane |
Contact List
Pierre Morsomme |
contact affiliation | Louvain Institute of Biomolecular Science and Technology (LIBST), UCLouvain, Belgium |
contact email | pierre.morsomme@uclouvain.be |
lab head | |
Jérôme Savocco |
contact affiliation | UCLouvain |
contact email | jerome.savocco@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD014695
- Label: PRIDE project
- Name: α-arrestin-dependent endocytosis after cycloheximide treatment