PXD014337-3

PXD014337 is an original dataset announced via ProteomeXchange.

Title	A synthetic crosslinked peptide library for benchmarking crosslinking mass spectrometry search engines
Description	We have created a synthetic crosslinked peptide library to benchmark crosslinking mass spectrometry search engines. The unique benefit of the library is knowing which identified crosslinks are true and which are false. The data collected from mass spectrometry measurements of the peptide library were used to assess the most frequently used search algorithms. The datasets included will provide an important resource for the crosslinking community to evaluate and optimise search engines, results from which have far-reaching implications.
HostingRepository	PRIDE
AnnounceDate	2020-11-06
AnnouncementXML	Submission_2020-11-06_08:30:41.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rebecca Beveridge
SpeciesList	scientific name: Streptococcus pyogenes ABC020006030; NCBI TaxID: 1438992;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos; Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-06-21 03:36:53	ID requested
1	2019-11-21 01:43:33	announced
2	2020-02-17 03:21:16	announced	2020-02-17: Updated publication reference for PubMed record(s): 32029734.
⏵ 3	2020-11-06 08:30:41	announced	2020-11-06: Updated project metadata.

Beveridge R, Stadlmann J, Penninger JM, Mechtler K, A synthetic peptide library for benchmarking crosslinking-mass spectrometry search engines for proteins and protein complexes. Nat Commun, 11(1):742(2020) [pubmed]

ProteomeXchange project tag: EPIC-XS

submitter keyword: crosslinking mass spectrometry peptide library

Karl Mechtler
contact affiliation	Institute for Molecular Pathology, Vienna, Austria. Institute of Molecular Biotechnology, Vienna Austria
contact email	karl.mechtler@imp.ac.at
lab head
Rebecca Beveridge
contact affiliation	Institute for Molecular Pathology
contact email	rebecca.beveridge@imp.ac.at
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/07/PXD014337

PRIDE project URI

• PRIDE
  1. PXD014337
     1. Label: PRIDE project
     2. Name: A synthetic crosslinked peptide library for benchmarking crosslinking mass spectrometry search engines