PXD014259-1

PXD014259 is an original dataset announced via ProteomeXchange.

Title	Serum protein profile in LPS-induced mice model by two-dimensional LC-MS/MS
Description	Serum is an ideal source of biomarkers because of easy accessibility, noninvasiveness, and rapid response to disease. Given that the different clinical manifestation between early phase and late phase of sepsis, the change of serum proteins profile during different phase of sepsis can give insight into predictor for early diagnosis of sepsis. In this study, differential serum proteins were screened in mice treated with lipopolysaccharide (LPS) for 2 h, 24 h and controls using free-labeling coupled with two-dimensional liquid chromatography and tandem mass spectrometry (2D LC-MS/MS) technique.
HostingRepository	PRIDE
AnnounceDate	2020-05-26
AnnouncementXML	Submission_2020-05-26_14:08:41.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Chunxia Wang
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-06-14 01:31:17	ID requested
⏵ 1	2020-05-26 14:08:42	announced
2	2024-10-22 05:05:29	announced	2024-10-22: Updated project metadata.

Wang C, Cui Y, Miao H, Xiong X, Dou J, Shao L, Tang X, Zhang Y, Apolipoprotein A-V Is a Novel Diagnostic and Prognostic Predictor in Pediatric Patients with Sepsis: A Prospective Pilot Study in PICU. Mediators Inflamm, 2020():8052954(2020) [pubmed]

submitter keyword: Protein profile, serum, LPS, mice, LC-MS/MS

Chunxia Wang
contact affiliation	Shanghai Children's Hospital
contact email	karencx0465@163.com
lab head
Chunxia Wang
contact affiliation	Shanghai Children's Hospital
contact email	karencx0465@163.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD014259
     1. Label: PRIDE project
     2. Name: Serum protein profile in LPS-induced mice model by two-dimensional LC-MS/MS