PXD014177 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic analysis of Mycobacterium tuberculosis induced by rifampicim |
Description | Rifampicin plays an important role during tuberculosis treatment, which historically contributed for shortening therapy; however, rifampicin resistance has been the intersection for the definition of multi (MDR-TB) and extensively (XDR-TB) resistant outcomes. A key aspect which has contributed for investigations of drug action/resistance is the understanding of the dynamic genome expression, as that analyzed by Proteomics. Proteins from the reference strain, Mycobacterium tuberculosis H37Rv were extracted after 12, 24 and 48 hours over rifampicin challenge at the minimal inhibitory concentration (0.03 μg•mL-1) and identified by LC-MS. |
HostingRepository | PRIDE |
AnnounceDate | 2021-05-04 |
AnnouncementXML | Submission_2021-05-04_05:41:23.014.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jean Eduardo Meneguello |
SpeciesList | scientific name: Mycobacterium tuberculosis H37Rv; NCBI TaxID: 83332; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | impact II |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-06-07 05:08:47 | ID requested | |
⏵ 1 | 2021-05-04 05:41:23 | announced | |
2 | 2021-05-04 22:20:58 | announced | 2021-05-05: Updated project metadata. |
Publication List
Keyword List
submitter keyword: proteomics, Mycobacterium tuberculosis, drug resistance, cell wall |
Contact List
Paula Aline Zanetti Campanerut-Sá |
contact affiliation | Postgraduate Program in Health Sciences, Center of Health Sciences, State University of Maringá, Maringá-PR, Brazil |
contact email | paulacampanerut@gmail.com |
lab head | |
Jean Eduardo Meneguello |
contact affiliation | State University of Maringá |
contact email | meneguello.je@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD014177
- Label: PRIDE project
- Name: Proteomic analysis of Mycobacterium tuberculosis induced by rifampicim