PXD013901 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Trypanosoma cruzi PAN 4 exosomes LC-MS/MS |
Description | Here we report the proteome content of exosomes released by epimastigote and bloodstream trypomastigotes forms of T. cruzi, the aetiological agent of Chagas disease. The exosomes were isolated using the ultracentrifugation method and further processed for LC-MS/MS. The results showed differential proteomic profiles of this two forms with marked differences in surface molecules cargoes. Noteworthy, the trans-sialidase (TS) surface proteins, a family of polymorphic virulence factors were differentially expressed between insect and human stages of T. cruzi highlighting the different surface nature of this two parasite stages. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-11 |
AnnouncementXML | Submission_2024-10-11_03:57:00.052.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD013901 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Luis Miguel de Pablos Torró |
SpeciesList | scientific name: Trypanosoma cruzi strain CL Brener; NCBI TaxID: 353153; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-05-17 05:18:55 | ID requested | |
⏵ 1 | 2024-10-11 03:57:00 | announced | |
Publication List
10.6019/PXD013901; |
Retana Moreira L, Prescilla-Ledezma A, Cornet-Gomez A, Linares F, J, ó, dar-Reyes AB, Fernandez J, Ibarrola Vannucci AK, De Pablos LM, Osuna A, . Int J Mol Sci, 22(10):(2021) [pubmed] |
10.3390/ijms22105183; |
Keyword List
submitter keyword: Exosomes, trypomastigote, Trypanosoma, epimastigote |
Contact List
Dr. Antonio Osuna |
contact affiliation | Instituto de Biotecnología, Grupo de Bioquímica y Parasitología Molecular, Departamento de Parasitología, Universidad de Granada, Granada, Spain. |
contact email | aosuna@ugr.es |
lab head | |
Luis Miguel de Pablos Torró |
contact affiliation | Universidad de Granada |
contact email | lpablos@ugr.es |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD013901 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD013901
- Label: PRIDE project
- Name: Trypanosoma cruzi PAN 4 exosomes LC-MS/MS