PXD013847-1

PXD013847 is an original dataset announced via ProteomeXchange.

Title	Role of Ssd1 in modulating protein abundance in aneuploid wild yeast
Description	We discovered that wild yeast strains can tolerate extra chromosomes, a condition known as aneuploidy, whereas well-studied laboratory strains cannot. Understanding why some cells can tolerate aneuploidy and others cannot could have far-reaching impact, as for example, 85% of solid tumors are aneuploidy and often benefit from extra chromosomes, and thus identifying mechanisms of aneuploidy sensitization could have therapeutic applications.
HostingRepository	PRIDE
AnnounceDate	2020-01-17
AnnouncementXML	Submission_2020-01-17_08:26:03.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Evgenia Shishkova
SpeciesList	scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2019-05-14 07:49:16	ID requested
⏵ 1	2020-01-17 08:26:04	announced
2	2024-10-22 04:56:52	announced	2024-10-22: Updated project metadata.

Hose J, Escalante LE, Clowers KJ, Dutcher HA, Robinson D, Bouriakov V, Coon JJ, Shishkova E, Gasch AP, The genetic basis of aneuploidy tolerance in wild yeast. Elife, 9():(2020) [pubmed]

submitter keyword: label-free proteomics, yeast, aneuploidy, SSD1

Joshua Coon
contact affiliation	University of Wisconsin - Madison
contact email	jcoon@chem.wisc.edu
lab head
Evgenia Shishkova
contact affiliation	University of Wisconsin - Madison
contact email	shishkova@wisc.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/01/PXD013847

PRIDE project URI

• PRIDE
  1. PXD013847
     1. Label: PRIDE project
     2. Name: Role of Ssd1 in modulating protein abundance in aneuploid wild yeast