PXD013769 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Cross-linking mass spectrometry of the CCAN and CCAN-Cenp-A complexes |
Description | Here we performed a cross-linking mass spectrometry analysis of the inner kinethocore complex CCAN and of the complex associated with a CenpA-nucleosome (CCAN-CenpA)from budding yeast. These experiments validated the cryo-EM structure of both complexes and provided additional structural insights on the complex organization. |
HostingRepository | PRIDE |
AnnounceDate | 2023-05-15 |
AnnouncementXML | Submission_2023-05-15_02:24:27.834.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | DomenicoFasci |
SpeciesList | scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-05-08 04:26:33 | ID requested | |
1 | 2019-08-20 04:47:42 | announced | |
2 | 2019-10-08 01:33:40 | announced | 2019-10-08: Updated publication reference for PubMed record(s): 31578520. |
⏵ 3 | 2023-05-15 02:24:28 | announced | 2023-05-15: Updated project metadata. |
Publication List
Yan K, Yang J, Zhang Z, McLaughlin SH, Chang L, Fasci D, Ehrenhofer-Murray AE, Heck AJR, Barford D, Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome. Nature, 574(7777):278-282(2019) [pubmed] |
Keyword List
ProteomeXchange project tag: EPIC-XS |
submitter keyword: S.Cerevisiae, cryo-EM structure,Inner kinetochore complex, XL-MS |
Contact List
Albert J.R.Heck |
contact affiliation | Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands |
contact email | A.J.R.Heck@uu.nl |
lab head | |
DomenicoFasci |
contact affiliation | Utrecht University |
contact email | d.fasci@uu.nl |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD013769
- Label: PRIDE project
- Name: Cross-linking mass spectrometry of the CCAN and CCAN-Cenp-A complexes