PXD013767 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Mass spectrometry of excretory/secretory products (ectosomes, exosomes, and soluble proteins) secreted by Toxoplasma gondii tachyzoites isolated from an infected murine model. |
Description | Toxoplasma gondii is an intracellular parasite that infects all nucleated cells; to date, this organism is considered as one of the most successful parasites in the world. During infection, internalization, and proliferation the parasite excretes/secretes a high number of proteins, several of them with identified roles, including MIC proteins, ROP proteins and GRA proteins involved in adhesion, invasion and intracellular proliferation respectively. The characterization of the secretome of Toxoplasma gondii opens the possibility to find new molecules for the design of future anti-parasitic strategies. The complete secretome and proteome of the parasite isolated from the murine model as well as their quantification by MS analysis are now available in the present report. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:50:13.957.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Emmanuel Rios-Castro |
SpeciesList | scientific name: Toxoplasma gondii GT1; NCBI TaxID: 507601; |
ModificationList | amidated residue; phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue |
Instrument | Synapt MS |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-05-08 04:25:10 | ID requested | |
1 | 2019-08-29 06:12:36 | announced | |
2 | 2019-08-29 07:47:14 | announced | Updated publication reference for PubMed record(s): 31434009. |
⏵ 3 | 2023-11-14 08:50:17 | announced | 2023-11-14: Updated project metadata. |
Publication List
Ram, í, rez-Flores CJ, Cruz-Mir, ó, n R, Mondrag, ó, n-Castel, á, n ME, Gonz, á, lez-Pozos S, R, í, os-Castro E, Mondrag, ó, n-Flores R, Proteomic and structural characterization of self-assembled vesicles from excretion/secretion products of Toxoplasma gondii. J Proteomics, 208():103490(2019) [pubmed] |
Keyword List
submitter keyword: Toxoplasma gondii., Quantification, Excretory/secretory products, Mass spectrometry,Ectosomes, Exosomes |
Contact List
Ricardo Mondragón-Flores |
contact affiliation | Department of Biochemistry, Cinvestav-IPN. |
contact email | rmflores@cinvestav.mx |
lab head | |
Emmanuel Rios-Castro |
contact affiliation | Cinvestav-IPN |
contact email | eriosc@cinvestav.mx |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD013767
- Label: PRIDE project
- Name: Mass spectrometry of excretory/secretory products (ectosomes, exosomes, and soluble proteins) secreted by Toxoplasma gondii tachyzoites isolated from an infected murine model.