PXD013609-2

PXD013609 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Oxidative stress in myelodysplastic syndromes
Description	Control of oxidative stress in the bone marrow (BM) is key for maintaining the balance between self-renewal, proliferation, and differentiation of hematopoietic cells. Breakdown of this regulation can lead to diseases characterized by BM failure such as the myelodysplastic syndromes (MDS). To better understand the role of oxidative stress in MDS development, we compared protein carbonylation as an oxidative stress marker in BM of patients with MDS and control subjects, and also patients with MDS under treatment with the iron chelator deferasirox.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:55:20.039.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Alba Rodriguez
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	4800 Plus MALDI TOF/TOF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2019-04-23 07:46:48	ID requested
1	2019-10-30 02:39:17	announced
⏵ 2	2024-10-22 04:55:22	announced	2024-10-22: Updated project metadata.

Publication List

10.3390/antiox8110508;
Rodr, í, guez-Garc, í, a A, Morales ML, Garrido-Garc, í, a V, Garc, í, a-Baquero I, Leivas A, Carre, ñ, o-Tarragona G, S, á, nchez R, Arenas A, Cedena T, Ayala RM, Bautista JM, Mart, í, nez-L, ó, pez J, Linares M, Protein Carbonylation in Patients with Myelodysplastic Syndrome: An Opportunity for Deferasirox Therapy. Antioxidants (Basel), 8(11):(2019) [pubmed]

10.3390/antiox8110508;

Rodr, í, guez-Garc, í, a A, Morales ML, Garrido-Garc, í, a V, Garc, í, a-Baquero I, Leivas A, Carre, ñ, o-Tarragona G, S, á, nchez R, Arenas A, Cedena T, Ayala RM, Bautista JM, Mart, í, nez-L, ó, pez J, Linares M, Protein Carbonylation in Patients with Myelodysplastic Syndrome: An Opportunity for Deferasirox Therapy. Antioxidants (Basel), 8(11):(2019) [pubmed]

Keyword List

submitter keyword: carbonylation, deferasirox, oxidative stress,Myelodysplastic syndromes

submitter keyword: carbonylation, deferasirox, oxidative stress,Myelodysplastic syndromes

Contact List

Joaquín Martínez
contact affiliation	Hospital Universitario 12 de Octubre
contact email	albarodriguezgarcia@hotmail.com
lab head
Alba Rodriguez
contact affiliation	Hospital 12 de Octubre
contact email	albarodriguezgarcia@hotmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/10/PXD013609
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/10/PXD013609

PRIDE project URI

Repository Record List

[ + ]