PXD013594-2

PXD013594 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Investigating the dynamics of the SecA–SecYEG complex dynamic by HDX-MS
Description	We employ hydrogen-deuterium exchange mass spectrometry (HDX-MS) to investigate the conformational dynamics required to facilitate based Brownian ratchet mechanism for protein secretion (by the SecA-SecYEG complex).
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:55:52.246.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zainab Ahdash
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	No PTMs are included in the dataset
Instrument	Synapt MS

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2019-04-23 02:45:46	ID requested
1	2019-07-16 04:33:57	announced
⏵ 2	2024-10-22 04:55:53	announced	2024-10-22: Updated project metadata.

Publication List

10.7554/elife.47402;
Ahdash Z, Pyle E, Allen WJ, Corey RA, Collinson I, Politis A, HDX-MS reveals nucleotide-dependent, anti-correlated opening and closure of SecA and SecY channels of the bacterial translocon. Elife, 8():(2019) [pubmed]

10.7554/elife.47402;

Ahdash Z, Pyle E, Allen WJ, Corey RA, Collinson I, Politis A, HDX-MS reveals nucleotide-dependent, anti-correlated opening and closure of SecA and SecY channels of the bacterial translocon. Elife, 8():(2019) [pubmed]

Keyword List

submitter keyword: SecA–SecYEG, HDX-MS

submitter keyword: SecA–SecYEG, HDX-MS

Contact List

Argyris Politis
contact affiliation	Lecturer in Chemical Systems Biology Department of Chemistry King's College London
contact email	argyris.politis@kcl.ac.uk
lab head
Zainab Ahdash
contact affiliation	King's College London
contact email	zainab.ahdash@kcl.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/07/PXD013594
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/07/PXD013594

PRIDE project URI

Repository Record List

[ + ]