PXD013343-1

PXD013343 is an original dataset announced via ProteomeXchange.

Title	Simple targeted assays for metabolic pathways and signaling: a powerful tool for targeted proteomics
Description	We introduce STAMPS, a pathway centric web service for the development of targeted proteomics assays. STAMPS guides the user by providing several intuitive interfaces for a rapid and simplified method design. Applying our curated framework to signaling and metabolic pathways, we reduced average assay development time by a factor of ~150 and revealed that the insulin signaling is actively controlled by protein abundance changes in insulin sensitive and resistance states.
HostingRepository	PRIDE
AnnounceDate	2024-10-07
AnnouncementXML	Submission_2024-10-07_13:29:40.080.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD013343
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Andreas Hentschel
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	Ammonia-loss; Gln->pyro-Glu; Glu->pyro-Glu; Oxidation; Carbamidomethyl; Acetyl
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2019-04-02 07:23:20	ID requested
⏵ 1	2024-10-07 13:29:45	announced

Kopczynski D, Hentschel A, Coman C, Schebb NH, Hornemann T, Mashek DG, Hartung NM, Shevchuk O, Sch, ö, tt HF, Lorenz K, Torta F, Burla B, Zahedi RP, Sickmann A, Kreutz MR, Ejsing CS, Medenbach J, Ahrends R, Simple Targeted Assays for Metabolic Pathways and Signaling: A Powerful Tool for Targeted Proteomics. Anal Chem, 92(20):13672-13676(2020) [pubmed]

10.1021/acs.analchem.0c02793;

curator keyword: Technical

submitter keyword: Databases,Proteomics, Mass spectrometry, Proteomic analysis

Albert Sickmann
contact affiliation	ISAS, Dortmund, Germany
contact email	albert.sickmann@isas.de
lab head
Andreas Hentschel
contact affiliation	Leibniz Institut für Analytische Wissenschaften
contact email	andreas.hentschel@isas.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/03/PXD013343

PRIDE project URI

• PRIDE
  1. PXD013343
     1. Label: PRIDE project
     2. Name: Simple targeted assays for metabolic pathways and signaling: a powerful tool for targeted proteomics