PXD012919-1
PXD012919 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Analysis of mitochondrial N termini by HUNTER (High-efficiency Undecanal-based N Termini EnRichment) |
| Description | Protein N-termini reveal fundamental regulatory mechanisms and their perturbation in disease. We present a robust, sensitive, scalable and automatable method called High-efficiency Undecanal-based N Termini EnRichment (HUNTER) for system-wide identification of thousands of N-termini from minute samples. Identification of distinct N-terminal profiles in mitochondrial-enriched B-ALL and AML samples as one of the applications of HUNTER. Mitochondria are enriched from 2.5 million cultured B-ALL or primary patient AML cells using pressure cycling (PCT) assisted lysis and differential density centrifugation. |
| HostingRepository | MassIVE |
| AnnounceDate | 2019-10-15 |
| AnnouncementXML | Submission_2019-10-15_10:54:12.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Philipp Lange |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | Acetyl; Dimethyl; Oxidation; Glu->pyro-Glu; Gln->pyro-Glu; Carbamidomethyl |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2019-02-28 17:57:32 | ID requested | |
| ⏵ 1 | 2019-10-15 10:54:13 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: HUNTER, N termini, proteolytic proteoforms, proteomics, mitochondrial, B-ALL, AML |
Contact List
| Dr. Pitter F. Huesgen | |
|---|---|
| contact affiliation | University of Cologne |
| contact email | p.huesgen@fz-juelich.de |
| lab head | |
| Dr. Philipp Lange | |
| contact affiliation | The University of British Columbia |
| contact email | philipp.lange@ubc.ca |
| lab head | |
| Philipp Lange | |
| contact affiliation | UBC |
| contact email | philipp.lange@ubc.ca |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000083504/ |
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