PXD012892 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Identification of human FGF9 IRES interacting proteins |
Description | We have previously shown that FGF9 is overexpressed in hypoxia through the IRES located in the 5’UTR. To identify the protein that binds to FGF9 IRES and controls FGF9 protein synthesis in hypoxia, FGF9 IRES RNA was in vitro synthesized and used to pulled-down interacting proteins. The RNA-protein complexes were first visualized by sliver staining, followed by cutting specific bands for protein identification using matrix-assisted laser desorption/ionization time-of-flight mass spectrometer (MALDI-TOF MS). |
HostingRepository | PRIDE |
AnnounceDate | 2019-11-13 |
AnnouncementXML | Submission_2019-11-12_18:57:21.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | H. Sunny Sun |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | ultraflex |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2019-02-27 06:25:54 | ID requested | |
⏵ 1 | 2019-11-12 18:57:23 | announced | |
2 | 2024-10-22 04:53:58 | announced | 2024-10-22: Updated project metadata. |
Publication List
Chen TM, Lai MC, Li YH, Chan YL, Wu CH, Wang YM, Chien CW, Huang SY, Sun HS, Tsai SJ, hnRNPM induces translation switch under hypoxia to promote colon cancer development. EBioMedicine, 41():299-309(2019) [pubmed] |
Keyword List
submitter keyword: Human, FGF9, IRES, hypoxia, MALDI-TOF MS |
Contact List
H. Sunny Sun |
contact affiliation | Center for Genomic Medicine, National Cheng Kung University, Tainan 70101, Taiwan; Institute of Molecular Medicine, National Cheng Kung University, Tainan 70101, Taiwan. |
contact email | hssun@mail.ncku.edu.tw |
lab head | |
H. Sunny Sun |
contact affiliation | H. Sunny Sun, Ph.D. Director and Professor, Institute of Molecular Medicine Director, Center for Genomic Medicine National Cheng Kung University Medical College 1 University road Tainan 70101, Taiwan PHONE: 886-6-2353535 ext. 3648, 3645 FAX: 886-6-2095845 email: hssun@mail.ncku.edu.tw |
contact email | hssun@mail.ncku.edu.tw |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD012892
- Label: PRIDE project
- Name: Identification of human FGF9 IRES interacting proteins