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PXD012892-1

PXD012892 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIdentification of human FGF9 IRES interacting proteins
DescriptionWe have previously shown that FGF9 is overexpressed in hypoxia through the IRES located in the 5’UTR. To identify the protein that binds to FGF9 IRES and controls FGF9 protein synthesis in hypoxia, FGF9 IRES RNA was in vitro synthesized and used to pulled-down interacting proteins. The RNA-protein complexes were first visualized by sliver staining, followed by cutting specific bands for protein identification using matrix-assisted laser desorption/ionization time-of-flight mass spectrometer (MALDI-TOF MS).
HostingRepositoryPRIDE
AnnounceDate2019-11-13
AnnouncementXMLSubmission_2019-11-12_18:57:21.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterH. Sunny Sun
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
Instrumentultraflex
Dataset History
RevisionDatetimeStatusChangeLog Entry
02019-02-27 06:25:54ID requested
12019-11-12 18:57:23announced
22024-10-22 04:53:58announced2024-10-22: Updated project metadata.
Publication List
Chen TM, Lai MC, Li YH, Chan YL, Wu CH, Wang YM, Chien CW, Huang SY, Sun HS, Tsai SJ, hnRNPM induces translation switch under hypoxia to promote colon cancer development. EBioMedicine, 41():299-309(2019) [pubmed]
Keyword List
submitter keyword: Human, FGF9, IRES, hypoxia, MALDI-TOF MS
Contact List
H. Sunny Sun
contact affiliationCenter for Genomic Medicine, National Cheng Kung University, Tainan 70101, Taiwan; Institute of Molecular Medicine, National Cheng Kung University, Tainan 70101, Taiwan.
contact emailhssun@mail.ncku.edu.tw
lab head
H. Sunny Sun
contact affiliationH. Sunny Sun, Ph.D. Director and Professor, Institute of Molecular Medicine Director, Center for Genomic Medicine National Cheng Kung University Medical College 1 University road Tainan 70101, Taiwan PHONE: 886-6-2353535 ext. 3648, 3645 FAX: 886-6-2095845 email: hssun@mail.ncku.edu.tw
contact emailhssun@mail.ncku.edu.tw
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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