PXD012875-1

PXD012875 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Selective abrogation of S6K2 maps lipid homeostasis as a survival vulnerability in MAPKi-resistant NRAS-mut melanoma
Description	These data support our manuscript "Selective abrogation of S6K2 maps lipid homeostasis as a survival vulnerability in MAPKi-resistant NRAS-mut melanoma". Proteomics was performed for M93-047 melanoma cells expressing vector control, S6K1 shRNA knockdown or S6K2 shRNA knockdown.
HostingRepository	MassIVE
AnnounceDate	2024-12-19
AnnouncementXML	Submission_2024-12-19_15:17:04.909.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Aaron Goldman
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	Oxidation; Carbamidomethyl; Acetyl
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2019-02-25 08:57:46	ID requested
⏵ 1	2024-12-19 15:17:05	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: MAPKi-resistance, NRAS, Melanoma, S6K2, S6K1, Lipid desaturation, Ferroptosis, Lipid peroxidation, Oxidative cell death, Cancer

submitter keyword: MAPKi-resistance, NRAS, Melanoma, S6K2, S6K1, Lipid desaturation, Ferroptosis, Lipid peroxidation, Oxidative cell death, Cancer

Contact List

Jessie Villanueva
contact affiliation	The Wistar Institute
contact email	jvillanueva@wistar.org
lab head
Aaron Goldman
contact affiliation	The Wistar Institute
contact email	agoldman@wistar.org
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v02/MSV000083480/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/v02/MSV000083480/