PXD012850-1

PXD012850 is an original dataset announced via ProteomeXchange.

Title	Pathologic alteration in the proteome of synaptosomes from the mouse model of spinal muscular atrophy
Description	In this study, label-free quantitative proteomic analysis was performed using the Smn 2B/- mouse model to identify and investigate significant changes in protein abundance that may be related to the pathogenesis and neurodegeneration oberved in spinal muscular atrophy (SMA)
HostingRepository	PRIDE
AnnounceDate	2019-07-04
AnnouncementXML	Submission_2019-07-04_11:47:21.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Robert Gombar
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue
Instrument	Synapt MS

Revision	Datetime	Status	ChangeLog Entry
0	2019-02-25 01:18:54	ID requested
⏵ 1	2019-07-04 11:47:23	announced

Eshraghi M, Gombar R, De Repentigny Y, Vacratsis PO, Kothary R, Pathologic Alterations in the Proteome of Synaptosomes from a Mouse Model of Spinal Muscular Atrophy. J Proteome Res, 18(8):3042-3051(2019) [pubmed]

curator keyword: Biomedical

submitter keyword: SMA, Label-free, Synapt, ion-mobility, synaptosomes

Panayiotis O. Vacratsis
contact affiliation	Chemistry and biochemistry, University of Windsor, Canada
contact email	vacratsi@uwindsor.ca
lab head
Robert Gombar
contact affiliation	University of Windsor
contact email	gombarr@uwindsor.ca
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/07/PXD012850

PRIDE project URI

• PRIDE
  1. PXD012850
     1. Label: PRIDE project
     2. Name: Pathologic alteration in the proteome of synaptosomes from the mouse model of spinal muscular atrophy