PXD012546-3

PXD012546 is an original dataset announced via ProteomeXchange.

Title	A Simple Cross-Linking/Mass Spectrometry Workflow to Study System-Wide Protein Interactions in Drosophila Embryos
Description	We provide a cross-linking/MS workflow that can be applied to complex systems. The software tool MeroX 2.0 can be used to identify cross-linked peptide on a proteome-wide level. We applied the workflow to extracts of Drosophila embryos and identified 5,129 unique cross-linked residue pairs in biological triplicates.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:52:44.465.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Michael Götze
SpeciesList	scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2019-01-29 01:18:58	ID requested
1	2019-07-09 05:07:45	announced
2	2019-07-15 06:49:16	announced	Updated publication reference for PubMed record(s): 31283178.
⏵ 3	2024-10-22 04:52:49	announced	2024-10-22: Updated project metadata.

10.1021/acs.analchem.9b02372;

G, ö, tze M, Iacobucci C, Ihling CH, Sinz A, A Simple Cross-Linking/Mass Spectrometry Workflow for Studying System-wide Protein Interactions. Anal Chem, 91(15):10236-10244(2019) [pubmed]

ProteomeXchange project tag: deep learning, benchmarking, machine learning

submitter keyword: cross-Linking, mass spectrometry, XLMS, CXMS, Drosophila

Andrea Sinz
contact affiliation	Department of Pharmaceutical Chemistry & Bioanalytics, Institute of Pharmacy, Charles Tanford Protein Center, Martin Luther University Halle-Wittenberg, Kurt-Mothes-Str. 3a, D-06120 Halle (Saale), Germany
contact email	andrea.sinz@pharmazie.uni-halle.de
lab head
Michael Götze
contact affiliation	Department of Biology
contact email	mgoetze@ethz.ch
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/07/PXD012546

PRIDE project URI

• PRIDE
  1. PXD012546
     1. Label: PRIDE project
     2. Name: A Simple Cross-Linking/Mass Spectrometry Workflow to Study System-Wide Protein Interactions in Drosophila Embryos