PXD012149-2

PXD012149 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Succinylome analysis reveals the involvement of lysine succinylation in extreme resistance of Deinococcus radiodurans
Description	Increasing evidences showing that succinylation of lysine residue mainly regulates enzymes involved in the carbon metabolism pathway, both in prokaryotic and eukaryotic cells. Deinococcus radiodurans is one of the most radioresistant organisms on earth, which is famous for its robust resistance. A major goal in the current study of protein succinylation is to explore its function in D. radiodurans. We used high-resolution liquid chromatography-mass spectrometry (LC-MS/MS) for qualitative proteomics to perform a global succinylation analysis of D. radiodurans and identified 492 succinylation sites on 270 proteins. These identified proteins are involved in a variety of biological process and pathways.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:21:24.884.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Congli Zhou
SpeciesList	scientific name: Deinococcus radiodurans; NCBI TaxID: 1299;
ModificationList	N6-succinyl-L-lysine
Instrument	Q Exactive Plus

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-12-21 02:36:46	ID requested
1	2021-04-25 21:34:12	announced
⏵ 2	2024-10-22 05:21:25	announced	2024-10-22: Updated project metadata.

Publication List

10.1002/pmic.201900158;
Zhou C, Dai J, Lu H, Chen Z, Guo M, He Y, Gao K, Ge T, Jin J, Wang L, Tian B, Hua Y, Zhao Y, Succinylome Analysis Reveals the Involvement of Lysine Succinylation in the Extreme Resistance of Deinococcus radiodurans. Proteomics, 19(20):e1900158(2019) [pubmed]

10.1002/pmic.201900158;

Zhou C, Dai J, Lu H, Chen Z, Guo M, He Y, Gao K, Ge T, Jin J, Wang L, Tian B, Hua Y, Zhao Y, Succinylome Analysis Reveals the Involvement of Lysine Succinylation in the Extreme Resistance of Deinococcus radiodurans. Proteomics, 19(20):e1900158(2019) [pubmed]

Keyword List

submitter keyword: succinylome
succinylation
DNA repair
Nucleic acid binding
posttranslational modification

submitter keyword: succinylome

succinylation

DNA repair

Nucleic acid binding

posttranslational modification

Contact List

Ye Zhao
contact affiliation	Key Laboratory of Chinese Ministry of Agriculture for Nuclear-Agricultural Sciences, Institute of Nuclear-Agricultural Sciences, Zhejiang University, China
contact email	yezhao@zju.edu.cn
lab head
Congli Zhou
contact affiliation	Zhejiang University
contact email	zhoucongli0628@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD012149
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD012149

PRIDE project URI

Repository Record List

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