PXD012075-1

PXD012075 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	HAP1 is an in vivo UBE3A Target that Augments Autophagy in a Mouse Model of Angelman Syndrome
Description	Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by maternal mutation and paternal imprinting of the gene encoding UBE3A, an E3 ubiquitin ligase. Although several potential target proteins of UBE3A have been reported, how these proteins regulate neuronal development remains unclear. We performed a large-scale quantitative proteomic analysis using stable-isotope labeling of amino acids in mammals (SILAM) on mice with maternal Ube3a mutation.
HostingRepository	MassIVE
AnnounceDate	2018-12-15
AnnouncementXML	Submission_2018-12-15_20:53:46.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	TingtingWang
SpeciesList	scientific name: Mus musculus;
ModificationList	No PTMs are included in the dataset
Instrument	instrument model: Q-Exactive( Thermo fisher)

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-12-15 18:40:18	ID requested
⏵ 1	2018-12-15 20:53:47	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: UBE3A SILAM autophagy

submitter keyword: UBE3A SILAM autophagy

Contact List

Lujian Liao
contact affiliation	Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University
contact email	ljliao@bio.ecnu.edu.cn
lab head
TingtingWang
contact affiliation	ECNU
contact email	wttecnu@163.com
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000083239

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000083239