PXD012068-1

PXD012068 is an original dataset announced via ProteomeXchange.

Title	Cyclin dependent kinase 5 (CDK5) regulates the circadian clock
Description	We show that the cyclin-dependent kinase 5 (CDK5) regulates the mammalian circadian clock via phosphorylation of PER2. CDK5 phosphorylated PER2 at serine residue 394 (S394) as shown by an in vitro kinase assay.
HostingRepository	PRIDE
AnnounceDate	2019-12-04
AnnouncementXML	Submission_2019-12-04_08:22:46.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Joern Dengjel
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	phosphorylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-12-14 03:46:41	ID requested
⏵ 1	2019-12-04 08:22:48	announced
2	2024-10-22 03:59:50	announced	2024-10-22: Updated project metadata.

Brenna A, Olejniczak I, Chavan R, Ripperger JA, Langmesser S, Cameroni E, Hu Z, De Virgilio C, Dengjel J, Albrecht U, Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock. Elife, 8():(2019) [pubmed]

curator keyword: Biological

submitter keyword: mouse, PER2, phosphorylation, in vitro kinase assay

Joern Dengjel
contact affiliation	Dr. Jörn Dengjel Prof. for Biochemistry and Cell Biology Department of Biology, University of Fribourg Chemin du Musée 10, 1700 Fribourg, Switzerland T +41 26 300 8631 E joern.dengjel@unifr.ch F +41 26 300 9741
contact email	joern.dengjel@unifr.ch
lab head
Joern Dengjel
contact affiliation	University of Fribourg
contact email	joern.dengjel@medizin.uni-freiburg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/12/PXD012068

PRIDE project URI

• PRIDE
  1. PXD012068
     1. Label: PRIDE project
     2. Name: Cyclin dependent kinase 5 (CDK5) regulates the circadian clock