PXD012051-1

PXD012051 is an original dataset announced via ProteomeXchange.

Title	Candida utilis as a protein source for Atlantic salmon
Description	Single cell proteins, such as Candida utilis, are known to have immunomodulating effects in the distal intestine (DI) of Atlantic salmon, whereas soybean meal (SBM) can cause soybean meal induce enteritis (SBMIE). Inflammatory or immunomodulatory stimuli at the local level in the intestine may alter the plasma protein profile of Atlantic salmon. These changes can be helpful tools in diagnosis for fish diseases and indicators for fish health. The present work aimed to identify local intestinal tissue responses and changes in plasma protein profiles of Atlantic salmon fed C. utilis yeast, SBM, or combined diets. Fish meal (FM) based diet was used as a control diet and the six experimental diets were: FM diet with 200 g/kg C. utilis (FM200CU) and five diets containing 200 g/kg SBM together with 0 (SBM group), 25, 50, 100 or 200 g/kg C. utilis (SBM25CU, SBM50CU, SBM100CU and SBM200CU groups, respectively). Intestine morphology of fish fed FM200CU where not affected whereas SBM group presented changes characteristic of SBMIE. Low inclusion of C. utilis in SBM diet showed a modulation of immune cell populations, but did not alleviate inflammatory symptom.
HostingRepository	PRIDE
AnnounceDate	2020-05-18
AnnouncementXML	Submission_2020-05-17_23:44:30.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Leidy Lagos
SpeciesList	scientific name: Salmo salar; NCBI TaxID: 8030;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-12-13 07:03:00	ID requested
⏵ 1	2020-05-17 23:44:31	announced

Reveco-Urzua FE, Hofoss, æ, ter M, Rao Kovi M, Mydland LT, Å, nestad R, S, ø, rby R, Press CM, Lagos L, Ø, verland M, Candida utilis yeast as a functional protein source for Atlantic salmon (Salmo salar L.): Local intestinal tissue and plasma proteome responses. PLoS One, 14(12):e0218360(2019) [pubmed]

submitter keyword: plasma proteome, histology, gene expression

Øverland, Margareth
contact affiliation	Department of Animal Sciences, Faculty of BIOVIT, Norwegian University of Life Sciences, Ås, Norway
contact email	margareth.overland@nmbu.no
lab head
Leidy Lagos
contact affiliation	Norwegian University of Life Sciences
contact email	leidy.lagos@nmbu.no
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/05/PXD012051

PRIDE project URI

• PRIDE
  1. PXD012051
     1. Label: PRIDE project
     2. Name: Candida utilis as a protein source for Atlantic salmon