PXD012044-1

PXD012044 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The Smarcal1-Usp37 locus modulates glycogen aggregation in astrocytes of the aged hippocampus
Description	This project aims to determine how genetic modifiers of normal cognitive aging impact cognitive, neurophysiological, and neurodegenerative changes in Alzheimer's disease models. Genetic variants in the BXD mouse model modulate the penetrance of 5XFAD mutations on the development and progression of cognitive defects. 40 strains from the BXD family of both males and females were collected from 6 months to 2 years of age and hippocampus tissue was collected for omics analysis.
HostingRepository	PRIDE
AnnounceDate	2026-01-23
AnnouncementXML	Submission_2026-01-23_07:29:22.220.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Evan Williams
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	No PTMs are included in the dataset
Instrument	TripleTOF 5600

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-12-13 01:45:06	ID requested
⏵ 1	2026-01-23 07:29:22	announced

Publication List

10.1016/J.CELS.2025.101488;

10.1016/J.CELS.2025.101488;

Keyword List

submitter keyword: None

submitter keyword: None

Contact List

Catherine Kaczorowski
contact affiliation	Associate Professor The Jackson Laboratory
contact email	Catherine.Kaczorowski@jax.org
lab head
Evan Williams
contact affiliation	ETH Zurich
contact email	evan.williams@uni.lu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD012044
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD012044

PRIDE project URI

Repository Record List

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