PXD012036-1

PXD012036 is an original dataset announced via ProteomeXchange.

Title	ROCK1 inhibition reduces steroid-refractory acute graft-versus-host disease
Description	To identify kinases in immune cells of patients with SR-GVHD we isolated leukocytes and specifically enriched kinases via kinet-beads-technology. Rho Kinase Type 1 (ROCK1) was identified as the most abundant kinase in SR-GVHD.
HostingRepository	PRIDE
AnnounceDate	2023-12-19
AnnouncementXML	Submission_2023-12-19_02:39:22.524.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Joern Dengjel
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-12-12 23:44:25	ID requested
⏵ 1	2023-12-19 02:39:22	announced
2	2024-10-22 06:18:03	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

curator keyword: Biomedical

submitter keyword: PBMC,kinase, graft-versus-host disease, human, ROCK1

Joern Dengjel
contact affiliation	Dr. Jörn Dengjel Prof. for Biochemistry and Cell Biology Department of Biology, University of Fribourg Chemin du Musée 10, 1700 Fribourg, Switzerland T +41 26 300 8631 E joern.dengjel@unifr.ch F +41 26 300 9741
contact email	joern.dengjel@unifr.ch
lab head
Joern Dengjel
contact affiliation	University of Fribourg
contact email	joern.dengjel@medizin.uni-freiburg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/12/PXD012036

PRIDE project URI

• PRIDE
  1. PXD012036
     1. Label: PRIDE project
     2. Name: ROCK1 inhibition reduces steroid-refractory acute graft-versus-host disease