PXD011901-2
PXD011901 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Hsa-miR-139-5p expression regulates the abundance of proteins related to poor survival cancer in CAL-62 thyroid cancer cell line |
Description | We studied the impact of hsa-miR-139-5p on the protein output by means of an iTRAQ-based approach. First, we established two CAL-62 isogenic cell lines expressing either the mature hsa-miR-139-5p or a non-targeting control upon a doxycycline inducible promoter (PTRE3G-tGFP, Dharmacon). Total proteins of P-tGFP-hsa-miR139-5p untreated or treated with doxycycline (1ug/ml) for 96 and 120 hours were isolated and labeled with iTRAQ® reagent 8-plex. Two independent experiments were performed. |
HostingRepository | PRIDE |
AnnounceDate | 2019-08-13 |
AnnouncementXML | Submission_2019-08-19_04:32:55.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Eduardo Zarzuela |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue |
Instrument | impact |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2018-11-30 05:01:24 | ID requested | |
1 | 2019-08-13 00:11:14 | announced | |
⏵ 2 | 2019-08-19 04:32:56 | announced | Updated publication reference for PubMed record(s): 31403184. |
Publication List
Montero-Conde C, Gra, ñ, a-Castro O, Mart, í, n-Serrano G, Mart, í, nez-Montes Á M, Zarzuela E, Mu, ñ, oz J, Torres-Perez R, Pita G, Cordero-Barreal A, Leandro-Garc, í, a LJ, Let, ó, n R, L, ó, pez de Silanes I, Guadalix S, P, é, rez-Barrios A, Hawkins F, Guerrero-, Á, lvarez A, Á, lvarez-Escol, á C, Regojo-Zapata RM, Calsina B, Remacha L, Rold, á, n-Romero JM, Santos M, Lanillos J, Jord, á M, Riesco-Eizaguirre G, Zafon C, Gonz, á, lez-Neira A, Blasco MA, Al-Shahrour F, Rodr, í, guez-Antona C, Casc, ó, n A, Robledo M, Hsa-miR-139-5p is a prognostic thyroid cancer marker involved in HNRNPF-mediated alternative splicing. Int J Cancer, 146(2):521-530(2020) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: Hsa-miR-139-5p, iTRAQ, Impact, CAL-62, thyroid cancer |
Contact List
Mercedes Robledo | |
---|---|
contact affiliation | CNIO |
contact email | mrobledo@cnio.es |
lab head | |
Eduardo Zarzuela | |
contact affiliation | Centro Nacional de Investigaciones Oncológicas |
contact email | eduzarfer@gmail.com |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/08/PXD011901 |
PRIDE project URI |
Repository Record List
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