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PXD011859-3

PXD011859 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMitochondrial mutant Caenorhabditis elegans phosphoproteome
DescriptionInhibition of insulin/IGF-1 signaling (IIS) represents a promising avenue for the treatment of mitochondrial diseases, although many of the molecular mechanisms underlying this beneficial effect remain elusive. Here, we investigate the phosphoproteomic landscape of Caenorhabditis elegans with severe mitochondrial deficiency in the context of insulin signaling inhibition.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:50:49.508.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAntonia Piazzesi
SpeciesList scientific name: Caenorhabditis elegans; NCBI TaxID: 6239;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue; phosphorylated residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-11-28 00:33:06ID requested
12019-02-13 04:02:58announced
22019-05-27 01:45:57announcedUpdated publication reference for PubMed record(s): 30796049.
32024-10-22 04:50:57announced2024-10-22: Updated project metadata.
Publication List
Gioran A, Piazzesi A, Bertan F, Schroer J, Wischhof L, Nicotera P, Bano D, dysfunction. EMBO J, 38(6):(2019) [pubmed]
10.15252/embj.201899558;
Keyword List
curator keyword: Biological
submitter keyword: metabolism,Caenorhabditis elegans, insulin signaling, Complex I, mitochondria, mitochondrial deficiency, IIS
Contact List
Daniele Bano
contact affiliationDZNE, Bonn, Germany
contact emailDaniele.Bano@dzne.de
lab head
Antonia Piazzesi
contact affiliationDZNE
contact emailAntonia.Piazzesi@dzne.de
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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