PXD011859-3
PXD011859 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Mitochondrial mutant Caenorhabditis elegans phosphoproteome |
Description | Inhibition of insulin/IGF-1 signaling (IIS) represents a promising avenue for the treatment of mitochondrial diseases, although many of the molecular mechanisms underlying this beneficial effect remain elusive. Here, we investigate the phosphoproteomic landscape of Caenorhabditis elegans with severe mitochondrial deficiency in the context of insulin signaling inhibition. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:50:49.508.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Antonia Piazzesi |
SpeciesList | scientific name: Caenorhabditis elegans; NCBI TaxID: 6239; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; phosphorylated residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2018-11-28 00:33:06 | ID requested | |
1 | 2019-02-13 04:02:58 | announced | |
2 | 2019-05-27 01:45:57 | announced | Updated publication reference for PubMed record(s): 30796049. |
⏵ 3 | 2024-10-22 04:50:57 | announced | 2024-10-22: Updated project metadata. |
Publication List
Gioran A, Piazzesi A, Bertan F, Schroer J, Wischhof L, Nicotera P, Bano D, dysfunction. EMBO J, 38(6):(2019) [pubmed] |
10.15252/embj.201899558; |
Keyword List
curator keyword: Biological |
submitter keyword: metabolism,Caenorhabditis elegans, insulin signaling, Complex I, mitochondria, mitochondrial deficiency, IIS |
Contact List
Daniele Bano | |
---|---|
contact affiliation | DZNE, Bonn, Germany |
contact email | Daniele.Bano@dzne.de |
lab head | |
Antonia Piazzesi | |
contact affiliation | DZNE |
contact email | Antonia.Piazzesi@dzne.de |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/02/PXD011859 |
PRIDE project URI |
Repository Record List
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