PXD011751-1

PXD011751 is an original dataset announced via ProteomeXchange.

Title	Interference of RNA molecules with protein aggregation in vitro.
Description	The analysis of RNA-protein interactomes indicates that the amount of structure in RNA molecules correlates with the capacity of binding to proteins in vitro and in vivo. To validate this observation, we used an in vitro network that mimics the composition of phase-separated RNA granules. The interference of external mRNA molecules on the protein composition of the network was analyzed by quantitative mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2019-09-13
AnnouncementXML	Submission_2019-09-13_03:28:35.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Giulia Calloni
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-11-20 01:07:20	ID requested
⏵ 1	2019-09-13 03:28:36	announced
2	2024-10-22 04:50:49	announced	2024-10-22: Updated project metadata.

Sanchez de Groot N, Armaos A, Gra, ñ, a-Montes R, Alriquet M, Calloni G, Vabulas RM, Tartaglia GG, RNA structure drives interaction with proteins. Nat Commun, 10(1):3246(2019) [pubmed]

curator keyword: Biological

submitter keyword: RNA granules, RNA interactivity, b-isox

R. Martin Vabulas
contact affiliation	Buchmann Institute of Molecular Life Sciences and Institute of Biophysical Chemistry, Goethe University, Frankfurt am Main, Germany
contact email	vabulas@em.uni-frankfurt.de
lab head
Giulia Calloni
contact affiliation	Goethe University Frankfurt
contact email	calloni@em.uni-frankfurt.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/09/PXD011751

PRIDE project URI

• PRIDE
  1. PXD011751
     1. Label: PRIDE project
     2. Name: Interference of RNA molecules with protein aggregation in vitro.